BDBM50125750 CHEMBL13910::N-[1-[2-(4-Butyryl-4-phenyl-piperidin-1-yl)-1-(4-methoxy-benzyl)-2-oxo-ethylcarbamoyl]-2-(1H-imidazol-4-yl)-ethyl]-benzamide

SMILES: CCCC(=O)C1(CCN(CC1)C(=O)[C@@H](Cc1ccc(OC)cc1)NC(=O)[C@@H](Cc1cnc[nH]1)NC(=O)c1ccccc1)c1ccccc1

InChI Key: InChIKey=LNJORQHQDHIPBT-CZNDPXEESA-N

Data: 1 IC50  4 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50125750   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Melanocortin receptor 3 (Homo sapiens (Human))	BDBM50125750 (CHEMBL13910 | N-[1-[2-(4-Butyryl-4-phenyl-piperidi...) Show SMILES CCCC(=O)C1(CCN(CC1)C(=O)[C@@H](Cc1ccc(OC)cc1)NC(=O)[C@@H](Cc1cnc[nH]1)NC(=O)c1ccccc1)c1ccccc1 Show InChI InChI=1S/C38H43N5O5/c1-3-10-34(44)38(29-13-8-5-9-14-29)19-21-43(22-20-38)37(47)33(23-27-15-17-31(48-2)18-16-27)42-36(46)32(24-30-25-39-26-40-30)41-35(45)28-11-6-4-7-12-28/h4-9,11-18,25-26,32-33H,3,10,19-24H2,1-2H3,(H,39,40)(H,41,45)(H,42,46)/t32-,33-/m1/s1	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	250	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL					Assay Description In vitro effective concentration towards human Melanocortin 3 receptor (MC3R) was determined by a SPA-based cAMP assay in melanoma cells				J Med Chem 46: 1123-6 (2003) Article DOI: 10.1021/jm025600i BindingDB Entry DOI: 10.7270/Q2KK9B43
					More data for this Ligand-Target Pair
Melanocyte-stimulating hormone receptor (Homo sapiens (Human))	BDBM50125750 (CHEMBL13910 | N-[1-[2-(4-Butyryl-4-phenyl-piperidi...) Show SMILES CCCC(=O)C1(CCN(CC1)C(=O)[C@@H](Cc1ccc(OC)cc1)NC(=O)[C@@H](Cc1cnc[nH]1)NC(=O)c1ccccc1)c1ccccc1 Show InChI InChI=1S/C38H43N5O5/c1-3-10-34(44)38(29-13-8-5-9-14-29)19-21-43(22-20-38)37(47)33(23-27-15-17-31(48-2)18-16-27)42-36(46)32(24-30-25-39-26-40-30)41-35(45)28-11-6-4-7-12-28/h4-9,11-18,25-26,32-33H,3,10,19-24H2,1-2H3,(H,39,40)(H,41,45)(H,42,46)/t32-,33-/m1/s1	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.10	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL					Assay Description In vitro inhibitory concentration of the compound against human Melanocortin 1 receptor (MC1R)				J Med Chem 46: 1123-6 (2003) Article DOI: 10.1021/jm025600i BindingDB Entry DOI: 10.7270/Q2KK9B43
					More data for this Ligand-Target Pair
Melanocortin receptor 5 (MC5R) (Homo sapiens (Human))	BDBM50125750 (CHEMBL13910 | N-[1-[2-(4-Butyryl-4-phenyl-piperidi...) Show SMILES CCCC(=O)C1(CCN(CC1)C(=O)[C@@H](Cc1ccc(OC)cc1)NC(=O)[C@@H](Cc1cnc[nH]1)NC(=O)c1ccccc1)c1ccccc1 Show InChI InChI=1S/C38H43N5O5/c1-3-10-34(44)38(29-13-8-5-9-14-29)19-21-43(22-20-38)37(47)33(23-27-15-17-31(48-2)18-16-27)42-36(46)32(24-30-25-39-26-40-30)41-35(45)28-11-6-4-7-12-28/h4-9,11-18,25-26,32-33H,3,10,19-24H2,1-2H3,(H,39,40)(H,41,45)(H,42,46)/t32-,33-/m1/s1	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	2.10E+3	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL					Assay Description In vitro effective concentration towards human Melanocortin 5 receptor (MC5R) was determined by a SPA-based cAMP assay in melanoma cells				J Med Chem 46: 1123-6 (2003) Article DOI: 10.1021/jm025600i BindingDB Entry DOI: 10.7270/Q2KK9B43
					More data for this Ligand-Target Pair
Melanocortin receptor 4 (Homo sapiens (Human))	BDBM50125750 (CHEMBL13910 | N-[1-[2-(4-Butyryl-4-phenyl-piperidi...) Show SMILES CCCC(=O)C1(CCN(CC1)C(=O)[C@@H](Cc1ccc(OC)cc1)NC(=O)[C@@H](Cc1cnc[nH]1)NC(=O)c1ccccc1)c1ccccc1 Show InChI InChI=1S/C38H43N5O5/c1-3-10-34(44)38(29-13-8-5-9-14-29)19-21-43(22-20-38)37(47)33(23-27-15-17-31(48-2)18-16-27)42-36(46)32(24-30-25-39-26-40-30)41-35(45)28-11-6-4-7-12-28/h4-9,11-18,25-26,32-33H,3,10,19-24H2,1-2H3,(H,39,40)(H,41,45)(H,42,46)/t32-,33-/m1/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	2.90	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL					Assay Description In vitro effective concentration towards human Melanocortin 4 receptor (MC4R) was determined by a SPA-based cAMP assay in melanoma cells				J Med Chem 46: 1123-6 (2003) Article DOI: 10.1021/jm025600i BindingDB Entry DOI: 10.7270/Q2KK9B43
					More data for this Ligand-Target Pair
Melanocyte-stimulating hormone receptor (Homo sapiens (Human))	BDBM50125750 (CHEMBL13910 | N-[1-[2-(4-Butyryl-4-phenyl-piperidi...) Show SMILES CCCC(=O)C1(CCN(CC1)C(=O)[C@@H](Cc1ccc(OC)cc1)NC(=O)[C@@H](Cc1cnc[nH]1)NC(=O)c1ccccc1)c1ccccc1 Show InChI InChI=1S/C38H43N5O5/c1-3-10-34(44)38(29-13-8-5-9-14-29)19-21-43(22-20-38)37(47)33(23-27-15-17-31(48-2)18-16-27)42-36(46)32(24-30-25-39-26-40-30)41-35(45)28-11-6-4-7-12-28/h4-9,11-18,25-26,32-33H,3,10,19-24H2,1-2H3,(H,39,40)(H,41,45)(H,42,46)/t32-,33-/m1/s1	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	0.190	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL					Assay Description In vitro inhibitory concentration against human Melanocortin 1 receptor (MC1R)				J Med Chem 46: 1123-6 (2003) Article DOI: 10.1021/jm025600i BindingDB Entry DOI: 10.7270/Q2KK9B43
					More data for this Ligand-Target Pair