BDBM50125902 (1S,4R)-4-(2-Benzhydryloxy-ethyl)-1-(4-fluoro-benzyl)-piperidin-3-ol::CHEMBL21213
SMILES: OC1CN(Cc2ccc(F)cc2)CC[C@@H]1CCOC(c1ccccc1)c1ccccc1
InChI Key: InChIKey=SEGLRXUOVKIQDG-FPSALIRRSA-N
Data: 4 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Sodium-dependent serotonin transporter (Rattus norvegicus (rat)) | BDBM50125902 ((1S,4R)-4-(2-Benzhydryloxy-ethyl)-1-(4-fluoro-benz...) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 3.60E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Wayne State University Curated by ChEMBL | Assay Description Binding affinity towards serotonin transporter in rat striatum using [3H]citalopram as radioligand | J Med Chem 46: 1220-8 (2003) Article DOI: 10.1021/jm020275k BindingDB Entry DOI: 10.7270/Q2CZ37XT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium-dependent dopamine transporter (Rattus norvegicus (rat)) | BDBM50125902 ((1S,4R)-4-(2-Benzhydryloxy-ethyl)-1-(4-fluoro-benz...) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 4.05 | n/a | n/a | n/a | n/a | n/a | n/a |
Wayne State University Curated by ChEMBL | Assay Description Inhibition of uptake from dopamine transporter in rat striatum using [3H]DA as radioligand | J Med Chem 46: 1220-8 (2003) Article DOI: 10.1021/jm020275k BindingDB Entry DOI: 10.7270/Q2CZ37XT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Norepinephrine Monoamine transporters (Rattus norvegicus) | BDBM50125902 ((1S,4R)-4-(2-Benzhydryloxy-ethyl)-1-(4-fluoro-benz...) | Reactome pathway KEGG UniProtKB/TrEMBL GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.88E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Wayne State University Curated by ChEMBL | Assay Description Binding affinity towards norepinephrine transporter in rat striatum using [3H]nisoxetine as radioligand | J Med Chem 46: 1220-8 (2003) Article DOI: 10.1021/jm020275k BindingDB Entry DOI: 10.7270/Q2CZ37XT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium-dependent dopamine transporter (Rattus norvegicus (rat)) | BDBM50125902 ((1S,4R)-4-(2-Benzhydryloxy-ethyl)-1-(4-fluoro-benz...) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 0.460 | n/a | n/a | n/a | n/a | n/a | n/a |
Wayne State University Curated by ChEMBL | Assay Description Binding affinity towards dopamine transporter in rat striatum using [3H]WIN-35 428 as radioligand | J Med Chem 46: 1220-8 (2003) Article DOI: 10.1021/jm020275k BindingDB Entry DOI: 10.7270/Q2CZ37XT | |||||||||||
More data for this Ligand-Target Pair |