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BDBM50125991 CHEMBL3627810

SMILES: COc1ccc(cc1)-n1c(CCN(C(C)=O)C(C)=O)nc2cc(Cl)ccc2c1=O

InChI Key: InChIKey=ZPALAZACKISLES-UHFFFAOYSA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50125991   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A


(Homo sapiens (Human))
BDBM50125991
PNG
(CHEMBL3627810)
Show SMILES COc1ccc(cc1)-n1c(CCN(C(C)=O)C(C)=O)nc2cc(Cl)ccc2c1=O
Show InChI InChI=1S/C21H20ClN3O4/c1-13(26)24(14(2)27)11-10-20-23-19-12-15(22)4-9-18(19)21(28)25(20)16-5-7-17(29-3)8-6-16/h4-9,12H,10-11H2,1-3H3
PDB
MMDB

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Similars

PubMed
45n/an/an/an/an/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
Inhibition of PDE10A (unknown origin)


Bioorg Med Chem Lett 25: 4893-8 (2015)


BindingDB Entry DOI: 10.7270/Q2RJ4M9Z
More data for this
Ligand-Target Pair