BDBM50126272 1-Isoquinolin-7-yl-3-phenyl-urea::CHEMBL283016

SMILES: O=C(Nc1ccccc1)Nc1ccc2ccncc2c1

InChI Key: InChIKey=BTZNFRFVCOSLGL-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50126272   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Inosine Monophosphate Dehydrogenase Type 2 (IMPDH2) (Homo sapiens (Human))	BDBM50126272 (1-Isoquinolin-7-yl-3-phenyl-urea | CHEMBL283016) Show SMILES O=C(Nc1ccccc1)Nc1ccc2ccncc2c1 Show InChI InChI=1S/C16H13N3O/c20-16(18-14-4-2-1-3-5-14)19-15-7-6-12-8-9-17-11-13(12)10-15/h1-11H,(H2,18,19,20)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	>5.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibitory activity of the compound against inosine 5'-inosine monophosphate dehydrogenase type II (IMPDH II)				Bioorg Med Chem Lett 13: 1345-8 (2003) BindingDB Entry DOI: 10.7270/Q2CV4H3Q
					More data for this Ligand-Target Pair