BDBM50126342 2'-Methyl-5-[(3-methyl-3H-imidazol-4-ylmethyl)-amino]-biphenyl-2-carbonitrile::CHEMBL27750

SMILES: Cc1ccccc1-c1cc(NCc2cncn2C)ccc1C#N

InChI Key: InChIKey=OADZPGZPQLMLJR-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50126342   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Protein Farnesyltransferase (PFT) (Bos taurus (bovine))	BDBM50126342 (2'-Methyl-5-[(3-methyl-3H-imidazol-4-ylmethyl)-ami...) Show SMILES Cc1ccccc1-c1cc(NCc2cncn2C)ccc1C#N Show InChI InChI=1S/C19H18N4/c1-14-5-3-4-6-18(14)19-9-16(8-7-15(19)10-20)22-12-17-11-21-13-23(17)2/h3-9,11,13,22H,12H2,1-2H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description In vitro inhibitory activity of the compound against farnesyltransferase (FTase)				Bioorg Med Chem Lett 13: 1367-71 (2003) BindingDB Entry DOI: 10.7270/Q20K27ZP
					More data for this Ligand-Target Pair