BDBM50126539 CHEMBL286779::N-{4-[4-(5-Chloro-thiophene-2-carbonyl)-piperazin-1-yl]-phenyl}-N-[3-(4-cyano-benzyl)-3H-imidazol-4-ylmethyl]-benzamide

SMILES: Clc1ccc(s1)C(=O)N1CCN(CC1)c1ccc(cc1)N(Cc1cncn1Cc1ccc(cc1)C#N)C(=O)c1ccccc1

InChI Key: InChIKey=UFQVUSBBKQNAAX-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50126539   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Protein Farnesyltransferase (PFT) (Bos taurus (bovine))	BDBM50126539 (CHEMBL286779 | N-{4-[4-(5-Chloro-thiophene-2-carbo...) Show SMILES Clc1ccc(s1)C(=O)N1CCN(CC1)c1ccc(cc1)N(Cc1cncn1Cc1ccc(cc1)C#N)C(=O)c1ccccc1 Show InChI InChI=1S/C34H29ClN6O2S/c35-32-15-14-31(44-32)34(43)39-18-16-38(17-19-39)28-10-12-29(13-11-28)41(33(42)27-4-2-1-3-5-27)23-30-21-37-24-40(30)22-26-8-6-25(20-36)7-9-26/h1-15,21,24H,16-19,22-23H2	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
Centre de Recherche Pierre Fabre Curated by ChEMBL					Assay Description Inhibit of purified bovine Farnesyl protein transferase.				Bioorg Med Chem Lett 13: 1455-8 (2003) BindingDB Entry DOI: 10.7270/Q2NV9JSG
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