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BDBM50126849 CHEMBL3628813

SMILES: COc1ccc-2c(SCc3cnc(Nc4ccccc4)nc-23)c1

InChI Key: InChIKey=NVEZMSZXHKLMSX-UHFFFAOYSA-N

Data: 1 IC50

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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50126849   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Vascular endothelial growth factor receptor


(Homo sapiens (human))
BDBM50126849
PNG
(CHEMBL3628813)
Show SMILES COc1ccc-2c(SCc3cnc(Nc4ccccc4)nc-23)c1
Show InChI InChI=1S/C18H15N3OS/c1-22-14-7-8-15-16(9-14)23-11-12-10-19-18(21-17(12)15)20-13-5-3-2-4-6-13/h2-10H,11H2,1H3,(H,19,20,21)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

PubMed
n/an/a>5.00E+4n/an/an/an/an/an/a



Universit£ di Pisa

Curated by ChEMBL


Assay Description
Inhibition of human KDR incubated for 50 mins by omnia tyr peptide 8 substrate based fluorescence assay


Citation and Details
More data for this
Ligand-Target Pair