BDBM50126951 CHEMBL3628956

SMILES: Cc1ccc2n3C[C@@](CCc3cc2c1)(NC(=O)c1c(Cl)cc(cc1Cl)-n1cnnc1)c1ccccc1

InChI Key: InChIKey=DAMMZTUDSVIXKV-MUUNZHRXSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50126951   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Coagulation factor IX (Homo sapiens (Human))	BDBM50126951 (CHEMBL3628956) Show SMILES Cc1ccc2n3C[C@@](CCc3cc2c1)(NC(=O)c1c(Cl)cc(cc1Cl)-n1cnnc1)c1ccccc1 |r| Show InChI InChI=1S/C28H23Cl2N5O/c1-18-7-8-25-19(11-18)12-21-9-10-28(15-35(21)25,20-5-3-2-4-6-20)33-27(36)26-23(29)13-22(14-24(26)30)34-16-31-32-17-34/h2-8,11-14,16-17H,9-10,15H2,1H3,(H,33,36)/t28-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	35	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of human F9a using CH3SO2-D-CHG-Gly-Arg-AFC.AcOH as substrate by fluorescence assay				Bioorg Med Chem Lett 25: 5437-43 (2015) BindingDB Entry DOI: 10.7270/Q2B859X6
					More data for this Ligand-Target Pair