BDBM50127071 5-[2-(2,5-Dihydroxy-phenyl)-ethyl]-N-[2-(4-fluoro-phenyl)-ethyl]-2-hydroxy-benzamide::CHEMBL44538

SMILES: Oc1ccc(O)c(CCc2ccc(O)c(c2)C(=O)NCCc2ccc(F)cc2)c1

InChI Key: InChIKey=TVGITUGUCMPDMS-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50127071   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tubulin alpha chain /beta chain (Bos taurus)	BDBM50127071 (5-[2-(2,5-Dihydroxy-phenyl)-ethyl]-N-[2-(4-fluoro-...) Show SMILES Oc1ccc(O)c(CCc2ccc(O)c(c2)C(=O)NCCc2ccc(F)cc2)c1 Show InChI InChI=1S/C23H22FNO4/c24-18-6-2-15(3-7-18)11-12-25-23(29)20-13-16(4-9-22(20)28)1-5-17-14-19(26)8-10-21(17)27/h2-4,6-10,13-14,26-28H,1,5,11-12H2,(H,25,29)	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	9.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
Purdue University Curated by ChEMBL					Assay Description Inhibition of tubulin polymerization was determined at 1.2 mg/mL concentration				J Med Chem 46: 1670-82 (2003) Article DOI: 10.1021/jm020292+ BindingDB Entry DOI: 10.7270/Q2HD7V1V
					More data for this Ligand-Target Pair