BDBM50127087 CHEMBL3628375

SMILES: c1n[nH]cc1-c1c[nH]c2ncc(nc12)-c1ccncc1

InChI Key: InChIKey=XFHBVLNFKZUSBX-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50127087   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mitogen-activated protein kinase 1 (Homo sapiens (Human))	BDBM50127087 (CHEMBL3628375) Show SMILES c1n[nH]cc1-c1c[nH]c2ncc(nc12)-c1ccncc1 Show InChI InChI=1S/C14H10N6/c1-3-15-4-2-9(1)12-8-17-14-13(20-12)11(7-16-14)10-5-18-19-6-10/h1-8H,(H,16,17)(H,18,19)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	354	n/a	n/a	n/a	n/a	n/a	n/a
Genentech Curated by ChEMBL					Assay Description Inhibition of ERK2 (unknown origin) using 5FAM-IPTSPITTTYFFFKKK as substrate after 1 hr by LC3K assay				Bioorg Med Chem Lett 25: 4728-32 (2015) BindingDB Entry DOI: 10.7270/Q2TB18QM
					More data for this Ligand-Target Pair