BDBM50127191 2-(8-(2-Fluoro-benzyl)-6-(3-methoxy-phenyl)-7-methyl-3-{[methyl-(2-pyridin-2-yl-ethyl)-amino]-methyl}-5-oxo-5,8-dihydro-imidazo[1,2-a]pyrimidin-2-yl)-2-methyl-propionic acid methyl ester::CHEMBL298982

SMILES: COC(=O)C(C)(C)c1nc2n(Cc3ccccc3F)c(C)c(-c3cccc(OC)c3)c(=O)n2c1CN(C)CCc1ccccn1

InChI Key: InChIKey=XYCILBLGOTVVJW-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50127191   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Gonadotropin releasing hormone 1 (GnRHR1) (Homo sapiens (Human))	BDBM50127191 (2-(8-(2-Fluoro-benzyl)-6-(3-methoxy-phenyl)-7-meth...) Show SMILES COC(=O)C(C)(C)c1nc2n(Cc3ccccc3F)c(C)c(-c3cccc(OC)c3)c(=O)n2c1CN(C)CCc1ccccn1 Show InChI InChI=1S/C35H38FN5O4/c1-23-30(24-13-11-15-27(20-24)44-5)32(42)41-29(22-39(4)19-17-26-14-9-10-18-37-26)31(35(2,3)33(43)45-6)38-34(41)40(23)21-25-12-7-8-16-28(25)36/h7-16,18,20H,17,19,21-22H2,1-6H3	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc. Curated by ChEMBL					Assay Description Binding affinity against human gonadotropin-releasing hormone receptor				J Med Chem 46: 1769-72 (2003) Article DOI: 10.1021/jm0205402 BindingDB Entry DOI: 10.7270/Q2474983
					More data for this Ligand-Target Pair