BDBM50127217 (E)-3-{2-Methyl-4-[4-methyl-2-(4-trifluoromethyl-phenyl)-thiazol-5-ylmethoxy]-phenyl}-acrylic acid::CHEMBL40614

SMILES: Cc1nc(sc1COc1ccc(\C=C\C(O)=O)c(C)c1)-c1ccc(cc1)C(F)(F)F

InChI Key: InChIKey=MRQBQZNVLNJRQR-UXBLZVDNSA-N

Data: 1 IC50  3 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50127217   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Peroxisome proliferator-activated receptor delta (Homo sapiens (Human))	BDBM50127217 ((E)-3-{2-Methyl-4-[4-methyl-2-(4-trifluoromethyl-p...) Show SMILES Cc1nc(sc1COc1ccc(\C=C\C(O)=O)c(C)c1)-c1ccc(cc1)C(F)(F)F Show InChI InChI=1S/C22H18F3NO3S/c1-13-11-18(9-5-15(13)6-10-20(27)28)29-12-19-14(2)26-21(30-19)16-3-7-17(8-4-16)22(23,24)25/h3-11H,12H2,1-2H3,(H,27,28)/b10-6+	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	PubMed	n/a	n/a	n/a	n/a	20	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Maximum transcriptional activation of human PPAR delta receptor				Bioorg Med Chem Lett 13: 1517-21 (2003) BindingDB Entry DOI: 10.7270/Q2VQ322G
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor alpha (PPAR alpha) (Homo sapiens (Human))	BDBM50127217 ((E)-3-{2-Methyl-4-[4-methyl-2-(4-trifluoromethyl-p...) Show SMILES Cc1nc(sc1COc1ccc(\C=C\C(O)=O)c(C)c1)-c1ccc(cc1)C(F)(F)F Show InChI InChI=1S/C22H18F3NO3S/c1-13-11-18(9-5-15(13)6-10-20(27)28)29-12-19-14(2)26-21(30-19)16-3-7-17(8-4-16)22(23,24)25/h3-11H,12H2,1-2H3,(H,27,28)/b10-6+	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	PubMed	n/a	n/a	n/a	n/a	3.20E+3	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Maximum transcriptional activation of human PPAR alpha receptor				Bioorg Med Chem Lett 13: 1517-21 (2003) BindingDB Entry DOI: 10.7270/Q2VQ322G
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor (Homo sapiens (Human))	BDBM50127217 ((E)-3-{2-Methyl-4-[4-methyl-2-(4-trifluoromethyl-p...) Show SMILES Cc1nc(sc1COc1ccc(\C=C\C(O)=O)c(C)c1)-c1ccc(cc1)C(F)(F)F Show InChI InChI=1S/C22H18F3NO3S/c1-13-11-18(9-5-15(13)6-10-20(27)28)29-12-19-14(2)26-21(30-19)16-3-7-17(8-4-16)22(23,24)25/h3-11H,12H2,1-2H3,(H,27,28)/b10-6+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	PubMed	n/a	n/a	n/a	n/a	2.70E+3	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Maximum transcriptional activation of human PPAR gamma receptor				Bioorg Med Chem Lett 13: 1517-21 (2003) BindingDB Entry DOI: 10.7270/Q2VQ322G
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor delta (Homo sapiens (Human))	BDBM50127217 ((E)-3-{2-Methyl-4-[4-methyl-2-(4-trifluoromethyl-p...) Show SMILES Cc1nc(sc1COc1ccc(\C=C\C(O)=O)c(C)c1)-c1ccc(cc1)C(F)(F)F Show InChI InChI=1S/C22H18F3NO3S/c1-13-11-18(9-5-15(13)6-10-20(27)28)29-12-19-14(2)26-21(30-19)16-3-7-17(8-4-16)22(23,24)25/h3-11H,12H2,1-2H3,(H,27,28)/b10-6+	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	PubMed	n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Binding affinity for human PPAR delta receptor				Bioorg Med Chem Lett 13: 1517-21 (2003) BindingDB Entry DOI: 10.7270/Q2VQ322G
					More data for this Ligand-Target Pair