BDBM50127219 CHEMBL39129::{4-[4-Methyl-2-(4-trifluoromethyl-phenyl)-thiazol-5-ylmethoxy]-phenyl}-acetic acid

SMILES: Cc1nc(sc1COc1ccc(CC(O)=O)cc1)-c1ccc(cc1)C(F)(F)F

InChI Key: InChIKey=IYDNASQEPFLDOU-UHFFFAOYSA-N

Data: 1 IC50  3 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50127219   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Peroxisome proliferator-activated receptor delta (Homo sapiens (Human))	BDBM50127219 (CHEMBL39129 | {4-[4-Methyl-2-(4-trifluoromethyl-ph...) Show SMILES Cc1nc(sc1COc1ccc(CC(O)=O)cc1)-c1ccc(cc1)C(F)(F)F Show InChI InChI=1S/C20H16F3NO3S/c1-12-17(11-27-16-8-2-13(3-9-16)10-18(25)26)28-19(24-12)14-4-6-15(7-5-14)20(21,22)23/h2-9H,10-11H2,1H3,(H,25,26)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	n/a	n/a	1.90E+3	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Maximum transcriptional activation of human PPAR delta receptor				Bioorg Med Chem Lett 13: 1517-21 (2003) BindingDB Entry DOI: 10.7270/Q2VQ322G
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor alpha (PPAR alpha) (Homo sapiens (Human))	BDBM50127219 (CHEMBL39129 | {4-[4-Methyl-2-(4-trifluoromethyl-ph...) Show SMILES Cc1nc(sc1COc1ccc(CC(O)=O)cc1)-c1ccc(cc1)C(F)(F)F Show InChI InChI=1S/C20H16F3NO3S/c1-12-17(11-27-16-8-2-13(3-9-16)10-18(25)26)28-19(24-12)14-4-6-15(7-5-14)20(21,22)23/h2-9H,10-11H2,1H3,(H,25,26)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	n/a	n/a	6.90E+3	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Maximum transcriptional activation of human PPAR alpha receptor				Bioorg Med Chem Lett 13: 1517-21 (2003) BindingDB Entry DOI: 10.7270/Q2VQ322G
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor (Homo sapiens (Human))	BDBM50127219 (CHEMBL39129 | {4-[4-Methyl-2-(4-trifluoromethyl-ph...) Show SMILES Cc1nc(sc1COc1ccc(CC(O)=O)cc1)-c1ccc(cc1)C(F)(F)F Show InChI InChI=1S/C20H16F3NO3S/c1-12-17(11-27-16-8-2-13(3-9-16)10-18(25)26)28-19(24-12)14-4-6-15(7-5-14)20(21,22)23/h2-9H,10-11H2,1H3,(H,25,26)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	n/a	n/a	7.90E+3	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Maximum transcriptional activation of human PPAR gamma receptor				Bioorg Med Chem Lett 13: 1517-21 (2003) BindingDB Entry DOI: 10.7270/Q2VQ322G
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor delta (Homo sapiens (Human))	BDBM50127219 (CHEMBL39129 | {4-[4-Methyl-2-(4-trifluoromethyl-ph...) Show SMILES Cc1nc(sc1COc1ccc(CC(O)=O)cc1)-c1ccc(cc1)C(F)(F)F Show InChI InChI=1S/C20H16F3NO3S/c1-12-17(11-27-16-8-2-13(3-9-16)10-18(25)26)28-19(24-12)14-4-6-15(7-5-14)20(21,22)23/h2-9H,10-11H2,1H3,(H,25,26)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Binding affinity for human PPAR delta receptor				Bioorg Med Chem Lett 13: 1517-21 (2003) BindingDB Entry DOI: 10.7270/Q2VQ322G
					More data for this Ligand-Target Pair