BDBM50127448 1-(5-Cyclohexyl-2-oxo-1-propyl-2,3-dihydro-1H-benzo[e][1,4]diazepin-3-yl)-3-[4-(4-pyridin-2-yl-piperazin-1-yl)-phenyl]-urea::CHEMBL298860

SMILES: CCCN1c2ccccc2C(=NC(NC(=O)Nc2ccc(cc2)N2CCN(CC2)c2ccccn2)C1=O)C1CCCCC1

InChI Key: InChIKey=ZRAARRPFSVHSME-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50127448   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Bradykinin B1 receptor (Homo sapiens (Human))	BDBM50127448 (1-(5-Cyclohexyl-2-oxo-1-propyl-2,3-dihydro-1H-benz...) Show SMILES CCCN1c2ccccc2C(=NC(NC(=O)Nc2ccc(cc2)N2CCN(CC2)c2ccccn2)C1=O)C1CCCCC1 |c:11| Show InChI InChI=1S/C34H41N7O2/c1-2-20-41-29-13-7-6-12-28(29)31(25-10-4-3-5-11-25)37-32(33(41)42)38-34(43)36-26-15-17-27(18-16-26)39-21-23-40(24-22-39)30-14-8-9-19-35-30/h6-9,12-19,25,32H,2-5,10-11,20-24H2,1H3,(H2,36,38,43)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	97.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of human bradykinin B1 receptor				J Med Chem 46: 1803-6 (2003) Article DOI: 10.1021/jm034020y BindingDB Entry DOI: 10.7270/Q29P32C6
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