BDBM50127522 2-Phenylacetylamino-pentanedioic acid 5-amide 1-{[2-(1H-indol-3-yl)-1-phenethylcarbamoyl-ethyl]-amide}::CHEMBL417947

SMILES: NC(=O)CCC(NC(=O)Cc1ccccc1)C(=O)NC(Cc1c[nH]c2ccccc12)C(=O)NCCc1ccccc1

InChI Key: InChIKey=BCRZWUKUZGBBLX-UHFFFAOYSA-N

Data: 3 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50127522   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
GRPR (Homo sapiens (Human))	BDBM50127522 (2-Phenylacetylamino-pentanedioic acid 5-amide 1-{[...) Show SMILES NC(=O)CCC(NC(=O)Cc1ccccc1)C(=O)NC(Cc1c[nH]c2ccccc12)C(=O)NCCc1ccccc1 Show InChI InChI=1S/C32H35N5O4/c33-29(38)16-15-27(36-30(39)19-23-11-5-2-6-12-23)32(41)37-28(20-24-21-35-26-14-8-7-13-25(24)26)31(40)34-18-17-22-9-3-1-4-10-22/h1-14,21,27-28,35H,15-20H2,(H2,33,38)(H,34,40)(H,36,39)(H,37,41)	KEGG UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.91E+4	n/a	n/a	n/a	n/a
Technische Universität München Curated by ChEMBL					Assay Description Effective concentration required against gastrin releasing peptide receptor (GRP-R) in CHO cells by using FLIPR assay				J Med Chem 46: 1918-30 (2003) Article DOI: 10.1021/jm0210921 BindingDB Entry DOI: 10.7270/Q29S1QDS
					More data for this Ligand-Target Pair
BRS3 (Homo sapiens (Human))	BDBM50127522 (2-Phenylacetylamino-pentanedioic acid 5-amide 1-{[...) Show SMILES NC(=O)CCC(NC(=O)Cc1ccccc1)C(=O)NC(Cc1c[nH]c2ccccc12)C(=O)NCCc1ccccc1 Show InChI InChI=1S/C32H35N5O4/c33-29(38)16-15-27(36-30(39)19-23-11-5-2-6-12-23)32(41)37-28(20-24-21-35-26-14-8-7-13-25(24)26)31(40)34-18-17-22-9-3-1-4-10-22/h1-14,21,27-28,35H,15-20H2,(H2,33,38)(H,34,40)(H,36,39)(H,37,41)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.20E+3	n/a	n/a	n/a	n/a
Technische Universität München Curated by ChEMBL					Assay Description Effective concentration required against human bombesin receptor 3 (BRS-3) in CHO cells by using FLIPR assay.				J Med Chem 46: 1918-30 (2003) Article DOI: 10.1021/jm0210921 BindingDB Entry DOI: 10.7270/Q29S1QDS
					More data for this Ligand-Target Pair
NMBR (Homo sapiens (Human))	BDBM50127522 (2-Phenylacetylamino-pentanedioic acid 5-amide 1-{[...) Show SMILES NC(=O)CCC(NC(=O)Cc1ccccc1)C(=O)NC(Cc1c[nH]c2ccccc12)C(=O)NCCc1ccccc1 Show InChI InChI=1S/C32H35N5O4/c33-29(38)16-15-27(36-30(39)19-23-11-5-2-6-12-23)32(41)37-28(20-24-21-35-26-14-8-7-13-25(24)26)31(40)34-18-17-22-9-3-1-4-10-22/h1-14,21,27-28,35H,15-20H2,(H2,33,38)(H,34,40)(H,36,39)(H,37,41)	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.50E+4	n/a	n/a	n/a	n/a
Technische Universität München Curated by ChEMBL					Assay Description Effective concentration required against nueromedin B receptor (NMB-R) in CHO cells by using FLIPR assay				J Med Chem 46: 1918-30 (2003) Article DOI: 10.1021/jm0210921 BindingDB Entry DOI: 10.7270/Q29S1QDS
					More data for this Ligand-Target Pair