| Reaction Details |
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 | Report a problem with these data |
| Target | Neuromedin-B receptor |
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| Ligand | BDBM50127522 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_141797 (CHEMBL748695) |
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| EC50 | 15000±n/a nM |
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| Citation |  Weber, D; Berger, C; Eickelmann, P; Antel, J; Kessler, H Design of selective peptidomimetic agonists for the human orphan receptor BRS-3. J Med Chem46:1918-30 (2003) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Neuromedin-B receptor |
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| Name: | Neuromedin-B receptor |
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| Synonyms: | Bombesin 1 | NMB-R | NMBR | NMBR_HUMAN | Neuromedin B | Neuromedin B receptor | Neuromedin-B receptor | Neuromedin-B-preferring bombesin receptor |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 43447.11 |
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| Organism: | Homo sapiens (Human) |
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| Description: | Bombesin 1 NMBR 0::P28336 |
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| Residue: | 390 |
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| Sequence: | MPSKSLSNLSVTTGANESGSVPEGWERDFLPASDGTTTELVIRCVIPSLYLLIITVGLLG
NIMLVKIFITNSAMRSVPNIFISNLAAGDLLLLLTCVPVDASRYFFDEWMFGKVGCKLIP
VIQLTSVGVSVFTLTALSADRYRAIVNPMDMQTSGALLRTCVKAMGIWVVSVLLAVPEAV
FSEVARISSLDNSSFTACIPYPQTDELHPKIHSVLIFLVYFLIPLAIISIYYYHIAKTLI
KSAHNLPGEYNEHTKKQMETRKRLAKIVLVFVGCFIFCWFPNHILYMYRSFNYNEIDPSL
GHMIVTLVARVLSFGNSCVNPFALYLLSESFRRHFNSQLCCGRKSYQERGTSYLLSSSAV
RMTSLKSNAKNMVTNSVLLNGHSMKQEMAL
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| BDBM50127522 |
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| n/a |
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| Name | BDBM50127522 |
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| Synonyms: | 2-Phenylacetylamino-pentanedioic acid 5-amide 1-{[2-(1H-indol-3-yl)-1-phenethylcarbamoyl-ethyl]-amide} | CHEMBL417947 |
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| Type | Small organic molecule |
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| Emp. Form. | C32H35N5O4 |
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| Mol. Mass. | 553.6514 |
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| SMILES | NC(=O)CCC(NC(=O)Cc1ccccc1)C(=O)NC(Cc1c[nH]c2ccccc12)C(=O)NCCc1ccccc1 |
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| Structure | 
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