BDBM50127558 1-(2,6-Difluoro-benzyl)-2-(2,6-difluoro-phenyl)-1H-benzoimidazole-4-carbaldehyde::1-(2,6-difluorobenzyl)-2-(2,6-difluorophenyl)-1H-benzo[d]imidazole-4-carbaldehyde::1-(2,6-difluorobenzyl)-2-(2,6-difluorophenyl)benzimidazole-4-carbaldehyde::CHEMBL59237

SMILES: Fc1cccc(F)c1Cn1c(nc2c(C=O)cccc12)-c1c(F)cccc1F

InChI Key: InChIKey=DABSVOFHWWOBPI-UHFFFAOYSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50127558   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Human immunodeficiency virus type 1 reverse transcriptase (Human immunodeficiency virus 1)	BDBM50127558 (1-(2,6-Difluoro-benzyl)-2-(2,6-difluoro-phenyl)-1H...) Show SMILES Fc1cccc(F)c1Cn1c(nc2c(C=O)cccc12)-c1c(F)cccc1F |(-3.52,-26.57,;-5.03,-26.26,;-6.04,-27.41,;-7.56,-27.1,;-8.04,-25.64,;-7.02,-24.49,;-7.5,-23.03,;-5.51,-24.81,;-4.49,-23.66,;-4.98,-22.2,;-4.08,-20.94,;-4.99,-19.7,;-6.45,-20.18,;-7.79,-19.42,;-7.79,-17.88,;-9.13,-17.11,;-9.12,-20.19,;-9.12,-21.74,;-7.79,-22.51,;-6.45,-21.73,;-2.54,-20.93,;-1.76,-22.26,;-2.53,-23.6,;-.22,-22.26,;.54,-20.92,;-.25,-19.58,;-1.78,-19.6,;-2.56,-18.27,)| Show InChI InChI=1S/C21H12F4N2O/c22-14-5-2-6-15(23)13(14)10-27-18-9-1-4-12(11-28)20(18)26-21(27)19-16(24)7-3-8-17(19)25/h1-9,11H,10H2	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	100	n/a	n/a	n/a	n/a
National Cancer Institute-Frederick Curated by ChEMBL					Assay Description Inhibition of HIV-1 reverse transcriptase.				J Med Chem 46: 1940-7 (2003) Article DOI: 10.1021/jm020271f BindingDB Entry DOI: 10.7270/Q2610ZPC
					More data for this Ligand-Target Pair