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SMILES: Brc1ccc(cc1)-c1cncc(c1)N1CC2CC(C1)N2

InChI Key: InChIKey=HDMBVSBKUKQIFS-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50127659   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Neuronal acetylcholine receptor subunit alpha-7


(Rattus norvegicus (Rat))		BDBM50127659
PNG
(CHEMBL3628500)
Show SMILES Brc1ccc(cc1)-c1cncc(c1)N1CC2CC(C1)N2
Show InChI InChI=1S/C16H16BrN3/c17-13-3-1-11(2-4-13)12-5-16(8-18-7-12)20-9-14-6-15(10-20)19-14/h1-5,7-8,14-15,19H,6,9-10H2
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PubMed
 3.40E+4n/an/an/an/an/an/an/an/a



University of Sassari

Curated by ChEMBL


Assay Description
Displacement of [125I]alpha-Bungarotoxin from alpha7 nAChR in Sprague-Dawley rat hippocampal membranes pre-incubated for 5 mins followed by overnight...

Eur J Med Chem 103: 429-37 (2015)


BindingDB Entry DOI: 10.7270/Q2HT2R5N
More data for this
Ligand-Target Pair