BindingDB logo
myBDB logout

null

SMILES: Nc1ncc(nc1CNC(=O)Nc1ccc(cc1)N(C(=O)c1ccccc1)c1ccccc1)C1CC1

InChI Key: InChIKey=ILWJRPMCZWTTKF-UHFFFAOYSA-N

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50127668   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
MAP kinase-activated protein kinase 2


(Homo sapiens (Human))		BDBM50127668
PNG
(CHEMBL3629333)
Show SMILES Nc1ncc(nc1CNC(=O)Nc1ccc(cc1)N(C(=O)c1ccccc1)c1ccccc1)C1CC1
Show InChI InChI=1S/C28H26N6O2/c29-26-25(33-24(17-30-26)19-11-12-19)18-31-28(36)32-21-13-15-23(16-14-21)34(22-9-5-2-6-10-22)27(35)20-7-3-1-4-8-20/h1-10,13-17,19H,11-12,18H2,(H2,29,30)(H2,31,32,36)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
PubMed
n/an/a 1.62E+4n/an/an/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
Inhibition of MK2 (unknown origin) by scintillation proximity assay

Bioorg Med Chem Lett 25: 5402-8 (2015)


BindingDB Entry DOI: 10.7270/Q28C9Z2S
More data for this
Ligand-Target Pair