BDBM50127703 CHEMBL3629696
SMILES: [Na+].[Na+].[Na+].CC(=O)NC[C@@H]1CCC(OP([O-])(=O)OC[C@H]2O[C@H]([C@H](O)[C@@H]2O)n2ccc(N)nc2=O)([C@H]1OCc1ccccc1)P([O-])([O-])=O
InChI Key: InChIKey=URQOEXYFGCDCTI-JIASGISESA-K
Data: 4 KI
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Beta-galactoside alpha-2,6-sialyltransferase 1 (Homo sapiens (Human)) | BDBM50127703 (CHEMBL3629696) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 28 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Peking University Curated by ChEMBL | Assay Description Inhibition of recombinant human N-terminal His-tagged ST6Gal-1 (44 to 406 residues) using CMP-Neu5Ac as substrate after 20 mins by UV/RP-HPLC method | J Med Chem 60: 2135-2141 (2017) Article DOI: 10.1021/acs.jmedchem.6b01644 BindingDB Entry DOI: 10.7270/Q2XP77Z0 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Beta-galactoside alpha-2,6-sialyltransferase 1 (Homo sapiens (Human)) | BDBM50127703 (CHEMBL3629696) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 28 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Peking University Curated by ChEMBL | Assay Description Competitive inhibition of human recombinant ST6Gal-1 using CMP-Neu5Ac and p-nitrophenyl LacNAc as donar and acceptor by Lineweaver-Burk double recipr... | J Med Chem 58: 7972-90 (2015) BindingDB Entry DOI: 10.7270/Q20V8FMQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Beta-galactoside alpha-2,6-sialyltransferase 1 (Homo sapiens (Human)) | BDBM50127703 (CHEMBL3629696) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 477 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Peking University Curated by ChEMBL | Assay Description Inhibition of recombinant human N-terminal His-tagged ST6Gal-1 (44 to 406 residues) using CMP-Neu5Ac as substrate after 20 mins by UV/RP-HPLC method | J Med Chem 60: 2135-2141 (2017) Article DOI: 10.1021/acs.jmedchem.6b01644 BindingDB Entry DOI: 10.7270/Q2XP77Z0 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Beta-galactoside alpha-2,6-sialyltransferase 1 (Homo sapiens (Human)) | BDBM50127703 (CHEMBL3629696) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 477 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Peking University Curated by ChEMBL | Assay Description Competitive inhibition of human recombinant ST6Gal-1 using CMP-Neu5Ac and p-nitrophenyl LacNAc as donar and acceptor by Lineweaver-Burk double recipr... | J Med Chem 58: 7972-90 (2015) BindingDB Entry DOI: 10.7270/Q20V8FMQ | |||||||||||
More data for this Ligand-Target Pair |