BDBM50127765 CHEMBL45645::[2-(2,2,2-Trifluoro-1-hydroxy-1-trifluoromethyl-ethyl)-naphthalen-1-yl]-carbamic acid isopropyl ester

SMILES: CC(C)OC(=O)Nc1c(ccc2ccccc12)C(O)(C(F)(F)F)C(F)(F)F

InChI Key: InChIKey=XSSONDGRICYENW-UHFFFAOYSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50127765   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sulfonylurea receptor 2, Kir6.2 (Homo sapiens (Human))	BDBM50127765 (CHEMBL45645 | [2-(2,2,2-Trifluoro-1-hydroxy-1-trif...) Show SMILES CC(C)OC(=O)Nc1c(ccc2ccccc12)C(O)(C(F)(F)F)C(F)(F)F Show InChI InChI=1S/C17H15F6NO3/c1-9(2)27-14(25)24-13-11-6-4-3-5-10(11)7-8-12(13)15(26,16(18,19)20)17(21,22)23/h3-9,26H,1-2H3,(H,24,25)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	n/a	n/a	1.16E+3	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Potassium channel opening activity in vitro using LtK cells transfected with Kir6.2/SUR2B exon 17				Bioorg Med Chem Lett 13: 1741-4 (2003) BindingDB Entry DOI: 10.7270/Q28S4P9V
					More data for this Ligand-Target Pair