BDBM50127790 3-Phenyl-N-[2-(2,2,2-trifluoro-1-hydroxy-1-trifluoromethyl-ethyl)-naphthalen-1-yl]-propionamide::CHEMBL48755

SMILES: OC(c1ccc2ccccc2c1NC(=O)CCc1ccccc1)(C(F)(F)F)C(F)(F)F

InChI Key: InChIKey=JSUYWDFYYXKFOZ-UHFFFAOYSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50127790   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sulfonylurea receptor 2, Kir6.2 (Homo sapiens (Human))	BDBM50127790 (3-Phenyl-N-[2-(2,2,2-trifluoro-1-hydroxy-1-trifluo...) Show SMILES OC(c1ccc2ccccc2c1NC(=O)CCc1ccccc1)(C(F)(F)F)C(F)(F)F Show InChI InChI=1S/C22H17F6NO2/c23-21(24,25)20(31,22(26,27)28)17-12-11-15-8-4-5-9-16(15)19(17)29-18(30)13-10-14-6-2-1-3-7-14/h1-9,11-12,31H,10,13H2,(H,29,30)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	1.75E+3	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Potassium channel opening activity in vitro using LtK cells transfected with Kir6.2/SUR2B exon 17				Bioorg Med Chem Lett 13: 1741-4 (2003) BindingDB Entry DOI: 10.7270/Q28S4P9V
					More data for this Ligand-Target Pair