BDBM50127805 2-Methyl-N-[2-(2,2,2-trifluoro-1-hydroxy-1-trifluoromethyl-ethyl)-naphthalen-1-yl]-benzamide::CHEMBL46435

SMILES: Cc1ccccc1C(=O)Nc1c(ccc2ccccc12)C(O)(C(F)(F)F)C(F)(F)F

InChI Key: InChIKey=VSQZHHMCQTVPFR-UHFFFAOYSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50127805   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sulfonylurea receptor 2, Kir6.2 (Homo sapiens (Human))	BDBM50127805 (2-Methyl-N-[2-(2,2,2-trifluoro-1-hydroxy-1-trifluo...) Show SMILES Cc1ccccc1C(=O)Nc1c(ccc2ccccc12)C(O)(C(F)(F)F)C(F)(F)F Show InChI InChI=1S/C21H15F6NO2/c1-12-6-2-4-8-14(12)18(29)28-17-15-9-5-3-7-13(15)10-11-16(17)19(30,20(22,23)24)21(25,26)27/h2-11,30H,1H3,(H,28,29)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	5.55E+3	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Potassium channel opening activity in vitro using LtK cells transfected with Kir6.2/SUR2B exon 17				Bioorg Med Chem Lett 13: 1741-4 (2003) BindingDB Entry DOI: 10.7270/Q28S4P9V
					More data for this Ligand-Target Pair