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BDBM50127831 2-[4-(3-Piperidin-1-yl-propoxy)-phenyl]-pyrazolo[1,5-a]pyridine::CHEMBL49156

SMILES: C(COc1ccc(cc1)-c1cc2ccccn2n1)CN1CCCCC1

InChI Key: InChIKey=KCNYNEUCOAMVDX-UHFFFAOYSA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50127831   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Histamine H3 receptor


(Homo sapiens (Human))		BDBM50127831
PNG
(2-[4-(3-Piperidin-1-yl-propoxy)-phenyl]-pyrazolo[1...)
Show SMILES C(COc1ccc(cc1)-c1cc2ccccn2n1)CN1CCCCC1
Show InChI InChI=1S/C21H25N3O/c1-3-12-23(13-4-1)14-6-16-25-20-10-8-18(9-11-20)21-17-19-7-2-5-15-24(19)22-21/h2,5,7-11,15,17H,1,3-4,6,12-14,16H2
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 11n/an/an/an/an/an/an/an/a



Johnson & Johnson Pharmaceutical Research and Development L. L. C.

Curated by ChEMBL


Assay Description
Binding affinity towards human Histamine H3 receptor using [3H]-N-methyl-histamine as radioligand

Bioorg Med Chem Lett 13: 1767-70 (2003)


BindingDB Entry DOI: 10.7270/Q21835V3
More data for this
Ligand-Target Pair