BDBM50127840 1-Ethyl-2-[4-(3-piperidin-1-yl-propoxy)-phenyl]-indolizine::CHEMBL49919

SMILES: CCc1c(cn2ccccc12)-c1ccc(OCCCN2CCCCC2)cc1

InChI Key: InChIKey=UUZOHNIUYVKMHS-UHFFFAOYSA-N

Data: 2 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50127840   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histamine H3 receptor (Homo sapiens (Human))	BDBM50127840 (1-Ethyl-2-[4-(3-piperidin-1-yl-propoxy)-phenyl]-in...) Show SMILES CCc1c(cn2ccccc12)-c1ccc(OCCCN2CCCCC2)cc1 Show InChI InChI=1S/C24H30N2O/c1-2-22-23(19-26-17-7-4-9-24(22)26)20-10-12-21(13-11-20)27-18-8-16-25-14-5-3-6-15-25/h4,7,9-13,17,19H,2-3,5-6,8,14-16,18H2,1H3	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	19	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Botswana Curated by ChEMBL					Assay Description Antagonist activity at human histamine H3 receptor				Eur J Med Chem 46: 5237-57 (2011) Article DOI: 10.1016/j.ejmech.2011.08.042 BindingDB Entry DOI: 10.7270/Q2ZG6SNF
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50127840 (1-Ethyl-2-[4-(3-piperidin-1-yl-propoxy)-phenyl]-in...) Show SMILES CCc1c(cn2ccccc12)-c1ccc(OCCCN2CCCCC2)cc1 Show InChI InChI=1S/C24H30N2O/c1-2-22-23(19-26-17-7-4-9-24(22)26)20-10-12-21(13-11-20)27-18-8-16-25-14-5-3-6-15-25/h4,7,9-13,17,19H,2-3,5-6,8,14-16,18H2,1H3	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	19	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical Research and Development L. L. C. Curated by ChEMBL					Assay Description Binding affinity towards human Histamine H3 receptor using [3H]-N-methyl-histamine as radioligand				Bioorg Med Chem Lett 13: 1767-70 (2003) BindingDB Entry DOI: 10.7270/Q21835V3
					More data for this Ligand-Target Pair