BDBM50127862 (R)-N*1*-[2-(1H-Indol-3-yl)-1-methylcarbamoyl-ethyl]-2-isobutyl-N*4*-pyridin-2-yl-succinamide::CHEMBL300902

SMILES: CNC(=O)C(Cc1c[nH]c2ccccc12)NC(=O)[C@H](CC(C)C)CC(=O)Nc1ccccn1

InChI Key: InChIKey=OORGRLDXMMAWSI-OQHSHRKDSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50127862   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Interstitial collagenase (Homo sapiens (Human))	BDBM50127862 ((R)-N*1*-[2-(1H-Indol-3-yl)-1-methylcarbamoyl-ethy...) Show SMILES CNC(=O)C(Cc1c[nH]c2ccccc12)NC(=O)[C@H](CC(C)C)CC(=O)Nc1ccccn1 Show InChI InChI=1S/C25H31N5O3/c1-16(2)12-17(14-23(31)30-22-10-6-7-11-27-22)24(32)29-21(25(33)26-3)13-18-15-28-20-9-5-4-8-19(18)20/h4-11,15-17,21,28H,12-14H2,1-3H3,(H,26,33)(H,29,32)(H,27,30,31)/t17-,21?/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	60	n/a	n/a	n/a	n/a	n/a	n/a
Université de Reims Champagne-Ardenne Curated by ChEMBL					Assay Description Inhibition of matrix metalloproteinase-1				Bioorg Med Chem Lett 13: 1783-6 (2003) BindingDB Entry DOI: 10.7270/Q2WH2PCT
					More data for this Ligand-Target Pair
72 kDa type IV collagenase (Homo sapiens (Human))	BDBM50127862 ((R)-N*1*-[2-(1H-Indol-3-yl)-1-methylcarbamoyl-ethy...) Show SMILES CNC(=O)C(Cc1c[nH]c2ccccc12)NC(=O)[C@H](CC(C)C)CC(=O)Nc1ccccn1 Show InChI InChI=1S/C25H31N5O3/c1-16(2)12-17(14-23(31)30-22-10-6-7-11-27-22)24(32)29-21(25(33)26-3)13-18-15-28-20-9-5-4-8-19(18)20/h4-11,15-17,21,28H,12-14H2,1-3H3,(H,26,33)(H,29,32)(H,27,30,31)/t17-,21?/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	50	n/a	n/a	n/a	n/a	n/a	n/a
Université de Reims Champagne-Ardenne Curated by ChEMBL					Assay Description Inhibition of Matrix metalloproteinase-2				Bioorg Med Chem Lett 13: 1783-6 (2003) BindingDB Entry DOI: 10.7270/Q2WH2PCT
					More data for this Ligand-Target Pair