BDBM50127877 3-{3-[2-(2-Chloro-ethoxy)-ethoxy]-phenyl}-4,5-dihydro-isoxazole-5-carboxylic acid (2'-sulfamoyl-biphenyl-4-yl)-amide::CHEMBL300908

SMILES: NS(=O)(=O)c1ccccc1-c1ccc(NC(=O)C2CC(=NO2)c2cccc(OCCOCCCl)c2)cc1

InChI Key: InChIKey=AZOZFKHHDNWACV-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50127877   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Coagulation factor X (Homo sapiens (Human))	BDBM50127877 (3-{3-[2-(2-Chloro-ethoxy)-ethoxy]-phenyl}-4,5-dihy...) Show SMILES NS(=O)(=O)c1ccccc1-c1ccc(NC(=O)C2CC(=NO2)c2cccc(OCCOCCCl)c2)cc1 |c:20| Show InChI InChI=1S/C26H26ClN3O6S/c27-12-13-34-14-15-35-21-5-3-4-19(16-21)23-17-24(36-30-23)26(31)29-20-10-8-18(9-11-20)22-6-1-2-7-25(22)37(28,32)33/h1-11,16,24H,12-15,17H2,(H,29,31)(H2,28,32,33)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	1.50E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Co. Curated by ChEMBL					Assay Description Binding affinity against the Factor Xa (FXa)				Bioorg Med Chem Lett 13: 1795-9 (2003) BindingDB Entry DOI: 10.7270/Q2N29WBV
					More data for this Ligand-Target Pair