BDBM50127890 3-p-Tolyl-4,5-dihydro-isoxazole-5-carboxylic acid (2'-sulfamoyl-biphenyl-4-yl)-amide::CHEMBL51785

SMILES: Cc1ccc(cc1)C1=NOC(C1)C(=O)Nc1ccc(cc1)-c1ccccc1S(N)(=O)=O

InChI Key: InChIKey=RWYRRHYQCAZVOQ-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50127890   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Coagulation factor X (Homo sapiens (Human))	BDBM50127890 (3-p-Tolyl-4,5-dihydro-isoxazole-5-carboxylic acid ...) Show SMILES Cc1ccc(cc1)C1=NOC(C1)C(=O)Nc1ccc(cc1)-c1ccccc1S(N)(=O)=O |t:8| Show InChI InChI=1S/C23H21N3O4S/c1-15-6-8-17(9-7-15)20-14-21(30-26-20)23(27)25-18-12-10-16(11-13-18)19-4-2-3-5-22(19)31(24,28)29/h2-13,21H,14H2,1H3,(H,25,27)(H2,24,28,29)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	2.10E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Co. Curated by ChEMBL					Assay Description Binding affinity against the Factor Xa (FXa)				Bioorg Med Chem Lett 13: 1795-9 (2003) BindingDB Entry DOI: 10.7270/Q2N29WBV
					More data for this Ligand-Target Pair