BDBM50127902 3-(4-Hydroxy-phenyl)-4,5-dihydro-isoxazole-5-carboxylic acid (2'-sulfamoyl-biphenyl-4-yl)-amide::CHEMBL298891

SMILES: NS(=O)(=O)c1ccccc1-c1ccc(NC(=O)C2CC(=NO2)c2ccc(O)cc2)cc1

InChI Key: InChIKey=QJMJIMCIHCYGLU-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50127902   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Coagulation factor X (Homo sapiens (Human))	BDBM50127902 (3-(4-Hydroxy-phenyl)-4,5-dihydro-isoxazole-5-carbo...) Show SMILES NS(=O)(=O)c1ccccc1-c1ccc(NC(=O)C2CC(=NO2)c2ccc(O)cc2)cc1 |c:20| Show InChI InChI=1S/C22H19N3O5S/c23-31(28,29)21-4-2-1-3-18(21)14-5-9-16(10-6-14)24-22(27)20-13-19(25-30-20)15-7-11-17(26)12-8-15/h1-12,20,26H,13H2,(H,24,27)(H2,23,28,29)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	2.20E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Co. Curated by ChEMBL					Assay Description Binding affinity against the Factor Xa (FXa)				Bioorg Med Chem Lett 13: 1795-9 (2003) BindingDB Entry DOI: 10.7270/Q2N29WBV
					More data for this Ligand-Target Pair