BDBM50127990 5-tert-Butyl-1-(4-fluoro-phenyl)-1H-indole::CHEMBL299590

SMILES: CC(C)(C)c1ccc2n(ccc2c1)-c1ccc(F)cc1

InChI Key: InChIKey=LKTSQUIZGWIGAG-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50127990   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM50127990 (5-tert-Butyl-1-(4-fluoro-phenyl)-1H-indole | CHEMB...) Show SMILES CC(C)(C)c1ccc2n(ccc2c1)-c1ccc(F)cc1 Show InChI InChI=1S/C18H18FN/c1-18(2,3)14-4-9-17-13(12-14)10-11-20(17)16-7-5-15(19)6-8-16/h4-12H,1-3H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Aventis Pharmaceuticals Curated by ChEMBL					Assay Description Inhibition of K+ channel activity in CHO cells expressing HERG Kv11.1				Bioorg Med Chem Lett 13: 1829-35 (2003) BindingDB Entry DOI: 10.7270/Q2TX3FX0
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM50127990 (5-tert-Butyl-1-(4-fluoro-phenyl)-1H-indole | CHEMB...) Show SMILES CC(C)(C)c1ccc2n(ccc2c1)-c1ccc(F)cc1 Show InChI InChI=1S/C18H18FN/c1-18(2,3)14-4-9-17-13(12-14)10-11-20(17)16-7-5-15(19)6-8-16/h4-12H,1-3H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TCG Lifesciences Ltd. Curated by ChEMBL					Assay Description Inhibition of human ERG				Eur J Med Chem 46: 618-30 (2011) Article DOI: 10.1016/j.ejmech.2010.11.042 BindingDB Entry DOI: 10.7270/Q2WQ052W
					More data for this Ligand-Target Pair