BDBM50128173 3-((3-(1,1,2,2-tetrafluoroethoxy)benzyl)(3-(4-chloro-3-methylphenoxy)phenyl)amino)-1,1,1-trifluoropropan-2-ol::3-((3-(4-chloro-3-methylphenoxy)phenyl)(3-(1,1,2,2-tetrafluoroethoxy)benzyl)amino)-1,1,1-trifluoropropan-2-ol::3-{[3-(4-Chloro-3-methyl-phenoxy)-phenyl]-[3-(1,1,2,2-tetrafluoro-ethoxy)-benzyl]-amino}-1,1,1-trifluoro-propan-2-ol::CHEMBL303937

SMILES: Cc1cc(Oc2cccc(c2)N(CC(O)C(F)(F)F)Cc2cccc(OC(F)(F)C(F)F)c2)ccc1Cl

InChI Key: InChIKey=BRLJUNDZVYTTDM-UHFFFAOYSA-N

Data: 4 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50128173   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cholesteryl ester transfer protein (Homo sapiens (Human))	BDBM50128173 (3-((3-(1,1,2,2-tetrafluoroethoxy)benzyl)(3-(4-chlo...) Show SMILES Cc1cc(Oc2cccc(c2)N(CC(O)C(F)(F)F)Cc2cccc(OC(F)(F)C(F)F)c2)ccc1Cl Show InChI InChI=1S/C25H21ClF7NO3/c1-15-10-19(8-9-21(15)26)36-18-6-3-5-17(12-18)34(14-22(35)24(29,30)31)13-16-4-2-7-20(11-16)37-25(32,33)23(27)28/h2-12,22-23,35H,13-14H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	200	n/a	n/a	n/a	n/a	n/a	n/a
Pharmacia Discovery Research (Pfizer Global Research and Development) Curated by ChEMBL					Assay Description Compound was tested in vitro for inhibitory activity against recombinant human cholesteryl ester transfer protein in buffer				J Med Chem 46: 2152-68 (2003) Article DOI: 10.1021/jm020528+ BindingDB Entry DOI: 10.7270/Q2QV3KWK
					More data for this Ligand-Target Pair
Cholesteryl ester transfer protein (Homo sapiens (Human))	BDBM50128173 (3-((3-(1,1,2,2-tetrafluoroethoxy)benzyl)(3-(4-chlo...) Show SMILES Cc1cc(Oc2cccc(c2)N(CC(O)C(F)(F)F)Cc2cccc(OC(F)(F)C(F)F)c2)ccc1Cl Show InChI InChI=1S/C25H21ClF7NO3/c1-15-10-19(8-9-21(15)26)36-18-6-3-5-17(12-18)34(14-22(35)24(29,30)31)13-16-4-2-7-20(11-16)37-25(32,33)23(27)28/h2-12,22-23,35H,13-14H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	2.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of CETP (unknown origin)-mediated [3H]cholesteryl ester transfer from HDL donor particles to LDL acceptor particles				Citation and Details Article DOI: 10.1007/s00044-004-0104-9 BindingDB Entry DOI: 10.7270/Q2SQ9387
					More data for this Ligand-Target Pair
Cholesteryl ester transfer protein (Oryctolagus cuniculus)	BDBM50128173 (3-((3-(1,1,2,2-tetrafluoroethoxy)benzyl)(3-(4-chlo...) Show SMILES Cc1cc(Oc2cccc(c2)N(CC(O)C(F)(F)F)Cc2cccc(OC(F)(F)C(F)F)c2)ccc1Cl Show InChI InChI=1S/C25H21ClF7NO3/c1-15-10-19(8-9-21(15)26)36-18-6-3-5-17(12-18)34(14-22(35)24(29,30)31)13-16-4-2-7-20(11-16)37-25(32,33)23(27)28/h2-12,22-23,35H,13-14H2,1H3	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	200	n/a	n/a	n/a	n/a	n/a	n/a
Al-Zaytoonah Private University of Jordan Curated by ChEMBL					Assay Description Inhibition of CETP in rabbit serum after 1 hr by fluorescent cholesteryl esters transfer assay				Eur J Med Chem 45: 1598-617 (2010) Article DOI: 10.1016/j.ejmech.2009.12.070 BindingDB Entry DOI: 10.7270/Q2VQ32VS
					More data for this Ligand-Target Pair
Cholesteryl ester transfer protein (Homo sapiens (Human))	BDBM50128173 (3-((3-(1,1,2,2-tetrafluoroethoxy)benzyl)(3-(4-chlo...) Show SMILES Cc1cc(Oc2cccc(c2)N(CC(O)C(F)(F)F)Cc2cccc(OC(F)(F)C(F)F)c2)ccc1Cl Show InChI InChI=1S/C25H21ClF7NO3/c1-15-10-19(8-9-21(15)26)36-18-6-3-5-17(12-18)34(14-22(35)24(29,30)31)13-16-4-2-7-20(11-16)37-25(32,33)23(27)28/h2-12,22-23,35H,13-14H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	200	n/a	n/a	n/a	n/a	n/a	n/a
Universidade Federal da Bahia Curated by ChEMBL					Assay Description Inhibition of CETP				Bioorg Med Chem 15: 6242-52 (2007) Article DOI: 10.1016/j.bmc.2007.06.021 BindingDB Entry DOI: 10.7270/Q2B857VG
					More data for this Ligand-Target Pair