BDBM50128194 (1R,3R)-4-(6-Amino-purin-9-yl)-cyclopent-2-enecarboxylic acid hydroxyamide::CHEMBL418883

SMILES: Nc1ncnc2n(cnc12)[C@H]1C[C@@H](C=C1)C(=O)NO

InChI Key: InChIKey=CJIKFXCNDDQKNZ-RNFRBKRXSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50128194   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Adenylate cyclase type 5 (Homo sapiens (Human))	BDBM50128194 ((1R,3R)-4-(6-Amino-purin-9-yl)-cyclopent-2-enecarb...) Show SMILES Nc1ncnc2n(cnc12)[C@H]1C[C@@H](C=C1)C(=O)NO |c:15| Show InChI InChI=1S/C11H12N6O2/c12-9-8-10(14-4-13-9)17(5-15-8)7-2-1-6(3-7)11(18)16-19/h1-2,4-7,19H,3H2,(H,16,18)(H2,12,13,14)/t6-,7-/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Millennium Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Inhibitory activity against recombinant human adenylate cyclase 5 expressed in HEK293 cells.				J Med Chem 46: 2177-86 (2003) Article DOI: 10.1021/jm0205604 BindingDB Entry DOI: 10.7270/Q2M32V44
					More data for this Ligand-Target Pair