BDBM50128195 (1R,3R)-[3-(6-Amino-purin-9-yl)-cyclopentyl]-acetic acid::CHEMBL67869

SMILES: Nc1ncnc2n(cnc12)[C@@H]1CC[C@@H](CC(O)=O)C1

InChI Key: InChIKey=IESMLMAYERQHOR-HTQZYQBOSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50128195   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Adenylate cyclase (Homo sapiens (Human))	BDBM50128195 ((1R,3R)-[3-(6-Amino-purin-9-yl)-cyclopentyl]-aceti...) Show SMILES Nc1ncnc2n(cnc12)[C@@H]1CC[C@@H](CC(O)=O)C1 Show InChI InChI=1S/C12H15N5O2/c13-11-10-12(15-5-14-11)17(6-16-10)8-2-1-7(3-8)4-9(18)19/h5-8H,1-4H2,(H,18,19)(H2,13,14,15)/t7-,8-/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	2.88E+4	n/a	n/a	n/a	n/a	n/a	n/a
Millennium Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Inhibitory activity against recombinant human adenylate cyclase 5 expressed in HEK293 cells.				J Med Chem 46: 2177-86 (2003) Article DOI: 10.1021/jm0205604 BindingDB Entry DOI: 10.7270/Q2M32V44
					More data for this Ligand-Target Pair