null
SMILES: CCc1ccc(o1)C(=O)Nc1ccc(N2C(=O)c3ccccc3C2=O)c(Cl)c1
InChI Key: InChIKey=VRJREUCZKVNRFD-UHFFFAOYSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Metabotropic glutamate receptor 1 (Homo sapiens (Human)) | BDBM50128230 (CHEMBL3628096) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a |
Vanderbilt University Curated by ChEMBL | Assay Description Positive allosteric modulation of human mGlu1 receptor in HEK293 cells assessed as potentiation of glutamate-induced calcium mobiliztion by Fluo-4AM ... | J Med Chem 58: 7959-71 (2015) BindingDB Entry DOI: 10.7270/Q2MK6FQ4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Metabotropic glutamate receptor 1 (Homo sapiens (Human)) | BDBM50128230 (CHEMBL3628096) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a |
Vanderbilt University Curated by ChEMBL | Assay Description Positive allosteric modulation of human mGlu1 receptor in HEK293 cells assessed as potentiation of glutamate-induced calcium mobiliztion by Fluo-4AM ... | J Med Chem 58: 7959-71 (2015) BindingDB Entry DOI: 10.7270/Q2MK6FQ4 | |||||||||||
More data for this Ligand-Target Pair |