BDBM50128387 (S)-1-[4-(5-Fluoro-3-methyl-benzo[b]thiophen-2-yl)-piperidin-1-yl]-3-(1H-indol-4-yloxy)-propan-2-ol::CHEMBL54890

SMILES: Cc1c(sc2ccc(F)cc12)C1CCN(C[C@H](O)COc2cccc3[nH]ccc23)CC1

InChI Key: InChIKey=IIIYSHZFBXJZLJ-IBGZPJMESA-N

Data: 1 KI

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Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50128387   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5-hydroxytryptamine receptor 1A (Homo sapiens (Human))	BDBM50128387 ((S)-1-[4-(5-Fluoro-3-methyl-benzo[b]thiophen-2-yl)...) Show SMILES Cc1c(sc2ccc(F)cc12)C1CCN(C[C@H](O)COc2cccc3[nH]ccc23)CC1 Show InChI InChI=1S/C25H27FN2O2S/c1-16-21-13-18(26)5-6-24(21)31-25(16)17-8-11-28(12-9-17)14-19(29)15-30-23-4-2-3-22-20(23)7-10-27-22/h2-7,10,13,17,19,27,29H,8-9,11-12,14-15H2,1H3/t19-/m0/s1	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	5.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Lilly Research Laboratories Curated by ChEMBL					Assay Description Binding affinity was determined towards 5-hydroxytryptamine 1A receptor receptor using [3H]-8-OH-DPAT as radioligand				Bioorg Med Chem Lett 13: 1903-5 (2003) BindingDB Entry DOI: 10.7270/Q2PV6JR6
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