BDBM50128463 (S)-2-{[1-((R)-2-Amino-3-mercapto-propionyl)-4-phenyl-piperidine-4-carbonyl]-amino}-4-methyl-pentanoic acid::CHEMBL58090

SMILES: CC(C)C[C@H](NC(=O)C1(CCN(CC1)C(=O)[C@@H](N)CS)c1ccccc1)C(O)=O

InChI Key: InChIKey=FLFNSORDYCBQRT-IRXDYDNUSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50128463   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Geranylgeranyl transferase type I beta subunit/Protein Farnesyltransferase (PFT) (Homo sapiens (Human))	BDBM50128463 ((S)-2-{[1-((R)-2-Amino-3-mercapto-propionyl)-4-phe...) Show SMILES CC(C)C[C@H](NC(=O)C1(CCN(CC1)C(=O)[C@@H](N)CS)c1ccccc1)C(O)=O Show InChI InChI=1S/C21H31N3O4S/c1-14(2)12-17(19(26)27)23-20(28)21(15-6-4-3-5-7-15)8-10-24(11-9-21)18(25)16(22)13-29/h3-7,14,16-17,29H,8-13,22H2,1-2H3,(H,23,28)(H,26,27)/t16-,17-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	<5	n/a	n/a	n/a	n/a	n/a	n/a
GPC Biotech, Inc. Curated by ChEMBL					Assay Description Inhibition of Candida albicans Geranylgeranyl transferase type I				Bioorg Med Chem Lett 13: 1935-7 (2003) BindingDB Entry DOI: 10.7270/Q2SN08CJ
					More data for this Ligand-Target Pair
Protein Farnesyltransferase (PFT) (Homo sapiens (Human))	BDBM50128463 ((S)-2-{[1-((R)-2-Amino-3-mercapto-propionyl)-4-phe...) Show SMILES CC(C)C[C@H](NC(=O)C1(CCN(CC1)C(=O)[C@@H](N)CS)c1ccccc1)C(O)=O Show InChI InChI=1S/C21H31N3O4S/c1-14(2)12-17(19(26)27)23-20(28)21(15-6-4-3-5-7-15)8-10-24(11-9-21)18(25)16(22)13-29/h3-7,14,16-17,29H,8-13,22H2,1-2H3,(H,23,28)(H,26,27)/t16-,17-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	200	n/a	n/a	n/a	n/a	n/a	n/a
GPC Biotech, Inc. Curated by ChEMBL					Assay Description Inhibition of Candida albicans Farnesyltransferase				Bioorg Med Chem Lett 13: 1935-7 (2003) BindingDB Entry DOI: 10.7270/Q2SN08CJ
					More data for this Ligand-Target Pair