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BDBM50128479 CHEMBL57186::[(2R,4S)-6-Fluoro-4-(4-fluoro-phenylamino)-2-methyl-3,4-dihydro-2H-quinolin-1-yl]-phenyl-methanone

SMILES: C[C@@H]1C[C@H](Nc2ccc(F)cc2)c2cc(F)ccc2N1C(=O)c1ccccc1

InChI Key: InChIKey=JLCWNRHNKUVWED-VFNWGFHPSA-N

Data: 1 EC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50128479   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Ecdysone receptor


(Aedes aegypti)		BDBM50128479
PNG
(CHEMBL57186 | [(2R,4S)-6-Fluoro-4-(4-fluoro-phenyl...)
Show SMILES C[C@@H]1C[C@H](Nc2ccc(F)cc2)c2cc(F)ccc2N1C(=O)c1ccccc1
Show InChI InChI=1S/C23H20F2N2O/c1-15-13-21(26-19-10-7-17(24)8-11-19)20-14-18(25)9-12-22(20)27(15)23(28)16-5-3-2-4-6-16/h2-12,14-15,21,26H,13H2,1H3/t15-,21+/m1/s1
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
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CHEMBL
PC cid
PC sid
UniChem

Similars
PubMed
n/an/an/an/a 1.73E+3n/an/an/an/a



RHeoGene

Curated by ChEMBL


Assay Description
Effective concentration for ecdysone-dependent transactivation in mammalian cell line expressing Aedes aegypti ecdysone receptor

Bioorg Med Chem Lett 13: 1943-6 (2003)


BindingDB Entry DOI: 10.7270/Q2NV9HN8
More data for this
Ligand-Target Pair