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BDBM50128485 CHEMBL291343::[(2R,4S)-6-Fluoro-4-(4-fluoro-phenylamino)-2-methyl-3,4-dihydro-2H-quinolin-1-yl]-(3-methoxy-phenyl)-methanone

SMILES: COc1cccc(c1)C(=O)N1[C@H](C)C[C@H](Nc2ccc(F)cc2)c2cc(F)ccc12

InChI Key: InChIKey=HIDPZDVJHQLXGQ-QRQCRPRQSA-N

Data: 1 EC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50128485   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Ecdysone receptor


(Aedes aegypti)		BDBM50128485
PNG
(CHEMBL291343 | [(2R,4S)-6-Fluoro-4-(4-fluoro-pheny...)
Show SMILES COc1cccc(c1)C(=O)N1[C@H](C)C[C@H](Nc2ccc(F)cc2)c2cc(F)ccc12
Show InChI InChI=1S/C24H22F2N2O2/c1-15-12-22(27-19-9-6-17(25)7-10-19)21-14-18(26)8-11-23(21)28(15)24(29)16-4-3-5-20(13-16)30-2/h3-11,13-15,22,27H,12H2,1-2H3/t15-,22+/m1/s1
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
PubMed
n/an/an/an/a 1.48E+3n/an/an/an/a



RHeoGene

Curated by ChEMBL


Assay Description
Effective concentration for ecdysone-dependent transactivation in mammalian cell line expressing Aedes aegypti ecdysone receptor

Bioorg Med Chem Lett 13: 1943-6 (2003)


BindingDB Entry DOI: 10.7270/Q2NV9HN8
More data for this
Ligand-Target Pair