BDBM50128616 3-(4-Diethylaminomethoxy-phenyl)-2-(4-furan-2-yl-benzenesulfonyl)-N-hydroxy-2-methyl-propionamide::CHEMBL310472
SMILES: CCN(CC)COc1ccc(CC(C)(C(=O)NO)S(=O)(=O)c2ccc(cc2)-c2ccco2)cc1
InChI Key: InChIKey=BLCLPMFYNMXITO-UHFFFAOYSA-N
Data: 3 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Interstitial collagenase (Homo sapiens (Human)) | BDBM50128616 (3-(4-Diethylaminomethoxy-phenyl)-2-(4-furan-2-yl-b...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents | Article PubMed | n/a | n/a | 14 | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth Research Curated by ChEMBL | Assay Description In vitro inhibition of matrix metalloprotease-1 | J Med Chem 46: 2361-75 (2003) Article DOI: 10.1021/jm0205548 BindingDB Entry DOI: 10.7270/Q2RR1ZZJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Collagenase 3 (Homo sapiens (Human)) | BDBM50128616 (3-(4-Diethylaminomethoxy-phenyl)-2-(4-furan-2-yl-b...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents | Article PubMed | n/a | n/a | 2 | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth Research Curated by ChEMBL | Assay Description In vitro inhibition of matrix metalloprotease-13 | J Med Chem 46: 2361-75 (2003) Article DOI: 10.1021/jm0205548 BindingDB Entry DOI: 10.7270/Q2RR1ZZJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Matrix metalloproteinase-9 (Homo sapiens (Human)) | BDBM50128616 (3-(4-Diethylaminomethoxy-phenyl)-2-(4-furan-2-yl-b...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents | Article PubMed | n/a | n/a | 4 | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth Research Curated by ChEMBL | Assay Description In vitro inhibition of matrix metalloprotease-9 | J Med Chem 46: 2361-75 (2003) Article DOI: 10.1021/jm0205548 BindingDB Entry DOI: 10.7270/Q2RR1ZZJ | |||||||||||
More data for this Ligand-Target Pair |