BDBM50128660 4-(4-Methoxy-benzenesulfonyl)-1-(3-phenyl-propyl)-piperidine-4-carboxylic acid hydroxyamide::CHEMBL312770::N-hydroxy-4-(4-methoxyphenylsulfonyl)-1-(3-phenylpropyl)piperidine-4-carboxamide

SMILES: COc1ccc(cc1)S(=O)(=O)C1(CCN(CCCc2ccccc2)CC1)C(=O)NO

InChI Key: InChIKey=FTWZRZIOCFAVKU-UHFFFAOYSA-N

Data: 4 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50128660   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Interstitial collagenase (Homo sapiens (Human))	BDBM50128660 (4-(4-Methoxy-benzenesulfonyl)-1-(3-phenyl-propyl)-...) Show SMILES COc1ccc(cc1)S(=O)(=O)C1(CCN(CCCc2ccccc2)CC1)C(=O)NO Show InChI InChI=1S/C22H28N2O5S/c1-29-19-9-11-20(12-10-19)30(27,28)22(21(25)23-26)13-16-24(17-14-22)15-5-8-18-6-3-2-4-7-18/h2-4,6-7,9-12,26H,5,8,13-17H2,1H3,(H,23,25)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.93E+3	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description In vitro inhibitory activity against matrix metalloprotease-1				J Med Chem 46: 2376-96 (2003) Article DOI: 10.1021/jm0205550 BindingDB Entry DOI: 10.7270/Q2N0178C
					More data for this Ligand-Target Pair
Matrix metalloproteinase-9 (Homo sapiens (Human))	BDBM50128660 (4-(4-Methoxy-benzenesulfonyl)-1-(3-phenyl-propyl)-...) Show SMILES COc1ccc(cc1)S(=O)(=O)C1(CCN(CCCc2ccccc2)CC1)C(=O)NO Show InChI InChI=1S/C22H28N2O5S/c1-29-19-9-11-20(12-10-19)30(27,28)22(21(25)23-26)13-16-24(17-14-22)15-5-8-18-6-3-2-4-7-18/h2-4,6-7,9-12,26H,5,8,13-17H2,1H3,(H,23,25)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	13	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description In vitro inhibitory activity against matrix metalloprotease-9.				J Med Chem 46: 2376-96 (2003) Article DOI: 10.1021/jm0205550 BindingDB Entry DOI: 10.7270/Q2N0178C
					More data for this Ligand-Target Pair
Disintegrin and metalloproteinase domain-containing protein 17 (Homo sapiens (Human))	BDBM50128660 (4-(4-Methoxy-benzenesulfonyl)-1-(3-phenyl-propyl)-...) Show SMILES COc1ccc(cc1)S(=O)(=O)C1(CCN(CCCc2ccccc2)CC1)C(=O)NO Show InChI InChI=1S/C22H28N2O5S/c1-29-19-9-11-20(12-10-19)30(27,28)22(21(25)23-26)13-16-24(17-14-22)15-5-8-18-6-3-2-4-7-18/h2-4,6-7,9-12,26H,5,8,13-17H2,1H3,(H,23,25)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	503	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description In vitro inhibitory activity against tumor necrosis factor alpha converting enzyme (TACE).				J Med Chem 46: 2376-96 (2003) Article DOI: 10.1021/jm0205550 BindingDB Entry DOI: 10.7270/Q2N0178C
					More data for this Ligand-Target Pair
Collagenase 3 (Homo sapiens (Human))	BDBM50128660 (4-(4-Methoxy-benzenesulfonyl)-1-(3-phenyl-propyl)-...) Show SMILES COc1ccc(cc1)S(=O)(=O)C1(CCN(CCCc2ccccc2)CC1)C(=O)NO Show InChI InChI=1S/C22H28N2O5S/c1-29-19-9-11-20(12-10-19)30(27,28)22(21(25)23-26)13-16-24(17-14-22)15-5-8-18-6-3-2-4-7-18/h2-4,6-7,9-12,26H,5,8,13-17H2,1H3,(H,23,25)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	11	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description In vitro inhibitory activity against matrix metalloprotease-13.				J Med Chem 46: 2376-96 (2003) Article DOI: 10.1021/jm0205550 BindingDB Entry DOI: 10.7270/Q2N0178C
					More data for this Ligand-Target Pair