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SMILES: CCCCN(CC)c1cc(C)nc2N(CC(=O)Nc12)c1ccc(Br)cc1CC

InChI Key: InChIKey=LWJXCUDUCRIMFR-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50128764   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Corticotropin-releasing factor receptor 1


(Homo sapiens (Human))		BDBM50128764
PNG
(CHEMBL3628729)
Show SMILES CCCCN(CC)c1cc(C)nc2N(CC(=O)Nc12)c1ccc(Br)cc1CC
Show InChI InChI=1S/C22H29BrN4O/c1-5-8-11-26(7-3)19-12-15(4)24-22-21(19)25-20(28)14-27(22)18-10-9-17(23)13-16(18)6-2/h9-10,12-13H,5-8,11,14H2,1-4H3,(H,25,28)
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 2.5n/an/an/an/an/an/an/an/a



Emory University

Curated by ChEMBL


Assay Description
Displacement of [125I]-Tyr0-sauvagine from human CRF1 receptor expressed in HEK293T cells after 2 hrs by scintillation counting

Bioorg Med Chem Lett 25: 5111-4 (2015)


BindingDB Entry DOI: 10.7270/Q2XW4MM0
More data for this
Ligand-Target Pair