BDBM50128832 CHEMBL3629357
SMILES: O[C@@H](CNCCc1ccc(CCN2CCC(Cn3cnc(n3)C(O)(c3ccccc3)c3ccccc3)CC2)cc1)c1ccc(O)c2[nH]c(=O)ccc12
InChI Key: InChIKey=HCEFKOKLPKFQMI-LHEWISCISA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Muscarinic acetylcholine receptor M3 (Homo sapiens (Human)) | BDBM50128832 (CHEMBL3629357) | Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 18 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Curated by ChEMBL | Assay Description Displacement of [3H]N-methyl scopolamine from human cloned muscarinic M3 receptor by dilution method | Bioorg Med Chem Lett 25: 5121-6 (2015) BindingDB Entry DOI: 10.7270/Q2JQ12V7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Beta-2 adrenergic receptor (Homo sapiens (Human)) | BDBM50128832 (CHEMBL3629357) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | n/a | n/a | 116 | n/a | n/a | n/a | n/a |
Pfizer Curated by ChEMBL | Assay Description Agonist activity at human beta2 adrenoceptor expressed in CHO cells assessed as stumulation of intracellular cAMP production | Bioorg Med Chem Lett 25: 5121-6 (2015) BindingDB Entry DOI: 10.7270/Q2JQ12V7 | |||||||||||
More data for this Ligand-Target Pair |