BDBM50128979 2-(3-Aza-bicyclo[3.2.2]non-3-yl)-1H-pyrrolo[3,2-b]pyridine-3-carbonitrile::CHEMBL303805

SMILES: N#Cc1c([nH]c2cccnc12)N1CC2CCC(CC2)C1

InChI Key: InChIKey=WPIBHKKDDHOPNG-UHFFFAOYSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50128979   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Calcium-activated potassium channel alpha/beta 1 (Homo sapiens (Human))	BDBM50128979 (2-(3-Aza-bicyclo[3.2.2]non-3-yl)-1H-pyrrolo[3,2-b]...) Show SMILES N#Cc1c([nH]c2cccnc12)N1CC2CCC(CC2)C1 |(7.82,.09,;7.33,-1.38,;6.86,-2.85,;7.77,-4.11,;6.86,-5.34,;5.4,-4.88,;4.07,-5.65,;2.73,-4.88,;2.73,-3.34,;4.07,-2.57,;5.4,-3.34,;9.31,-4.18,;10.13,-2.89,;11.67,-2.71,;12.75,-3.81,;12.6,-5.34,;11.29,-6.16,;10.48,-4.88,;10.53,-3.72,;9.82,-5.65,)| Show InChI InChI=1S/C16H18N4/c17-8-13-15-14(2-1-7-18-15)19-16(13)20-9-11-3-4-12(10-20)6-5-11/h1-2,7,11-12,19H,3-6,9-10H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	4.43E+3	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description [86Rb+] efflux induced by BKca alpha subunits expressed in HEK293 cells at 10 microM				Bioorg Med Chem Lett 13: 2003-7 (2003) BindingDB Entry DOI: 10.7270/Q2QN6647
					More data for this Ligand-Target Pair