BDBM50128981 1-(3-Cyano-1H-pyrrolo[3,2-b]pyridin-2-yl)-piperidine-4-carboxylic acid methyl ester::CHEMBL303577

SMILES: COC(=O)C1CCN(CC1)c1[nH]c2cccnc2c1C#N

InChI Key: InChIKey=QNBLGBIECAIAQI-UHFFFAOYSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50128981   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Calcium-activated potassium channel alpha/beta 1 (Homo sapiens (Human))	BDBM50128981 (1-(3-Cyano-1H-pyrrolo[3,2-b]pyridin-2-yl)-piperidi...) Show SMILES COC(=O)C1CCN(CC1)c1[nH]c2cccnc2c1C#N Show InChI InChI=1S/C15H16N4O2/c1-21-15(20)10-4-7-19(8-5-10)14-11(9-16)13-12(18-14)3-2-6-17-13/h2-3,6,10,18H,4-5,7-8H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	1.70E+4	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description [86Rb+] efflux induced by BKca alpha subunits expressed in HEK293 cells at 10 microM				Bioorg Med Chem Lett 13: 2003-7 (2003) BindingDB Entry DOI: 10.7270/Q2QN6647
					More data for this Ligand-Target Pair