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SMILES: COc1ccc(cc1)N1CCN(CC1)c1cc(ccc1CNC(=O)C(C)c1ccc(NS(C)(=O)=O)c(F)c1)C(F)(F)F

InChI Key: InChIKey=JALAOUUCVOKBPN-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50129009   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Transient receptor potential cation channel subfamily V member 1


(Homo sapiens (Human))		BDBM50129009
PNG
(CHEMBL3627933)
Show SMILES COc1ccc(cc1)N1CCN(CC1)c1cc(ccc1CNC(=O)C(C)c1ccc(NS(C)(=O)=O)c(F)c1)C(F)(F)F
Show InChI InChI=1S/C29H32F4N4O4S/c1-19(20-5-11-26(25(30)16-20)35-42(3,39)40)28(38)34-18-21-4-6-22(29(31,32)33)17-27(21)37-14-12-36(13-15-37)23-7-9-24(41-2)10-8-23/h4-11,16-17,19,35H,12-15,18H2,1-3H3,(H,34,38)
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PubMed
 1.60n/an/an/an/an/an/an/an/a



Seoul National University

Curated by ChEMBL


Assay Description
Antagonist activity at human TRPV1 heterologously expressed in CHO cells assessed as inhibition of capsaicin-induced activation by FLIPR assay

Bioorg Med Chem 23: 6844-54 (2015)


BindingDB Entry DOI: 10.7270/Q2DZ0B4X
More data for this
Ligand-Target Pair