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SMILES: CC(C(=O)NCc1ccc(cc1OCc1ccccc1)C(F)(F)F)c1ccc(NS(C)(=O)=O)c(F)c1

InChI Key: InChIKey=PIWZRMSKHHJFKX-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50129029   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Transient receptor potential cation channel subfamily V member 1


(Homo sapiens (Human))		BDBM50129029
PNG
(CHEMBL3627943)
Show SMILES CC(C(=O)NCc1ccc(cc1OCc1ccccc1)C(F)(F)F)c1ccc(NS(C)(=O)=O)c(F)c1
Show InChI InChI=1S/C25H24F4N2O4S/c1-16(18-9-11-22(21(26)12-18)31-36(2,33)34)24(32)30-14-19-8-10-20(25(27,28)29)13-23(19)35-15-17-6-4-3-5-7-17/h3-13,16,31H,14-15H2,1-2H3,(H,30,32)
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MMDB

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PC cid
PC sid
UniChem
PubMed
 0.900n/an/an/an/an/an/an/an/a



Seoul National University

Curated by ChEMBL


Assay Description
Antagonist activity at human TRPV1 heterologously expressed in CHO cells assessed as inhibition of capsaicin-induced activation by FLIPR assay

Bioorg Med Chem 23: 6844-54 (2015)


BindingDB Entry DOI: 10.7270/Q2DZ0B4X
More data for this
Ligand-Target Pair