BDBM50129088 CHEMBL62355::N-Methyl-N'-(4-oxazol-5-yl-phenyl)-6-phenyl-[1,3,5]triazine-2,4-diamine

SMILES: CNc1nc(Nc2ccc(cc2)-c2cnco2)nc(n1)-c1ccccc1

InChI Key: InChIKey=HMUXKXVYTIQXSJ-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50129088   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Inosine Monophosphate Dehydrogenase Type 2 (IMPDH2) (Homo sapiens (Human))	BDBM50129088 (CHEMBL62355 | N-Methyl-N'-(4-oxazol-5-yl-phenyl)-6...) Show SMILES CNc1nc(Nc2ccc(cc2)-c2cnco2)nc(n1)-c1ccccc1 Show InChI InChI=1S/C19H16N6O/c1-20-18-23-17(14-5-3-2-4-6-14)24-19(25-18)22-15-9-7-13(8-10-15)16-11-21-12-26-16/h2-12H,1H3,(H2,20,22,23,24,25)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	>5.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibition of inosine-5'-monophosphate dehydrogenase 2.				Bioorg Med Chem Lett 13: 2059-63 (2003) BindingDB Entry DOI: 10.7270/Q22Z14X1
					More data for this Ligand-Target Pair