BDBM50129106 CHEMBL63122::N-{2-[2-(3-Chloro-4-oxazol-5-yl-phenylamino)-oxazol-5-yl]-phenyl}-2-hydroxy-N-methyl-acetamide

SMILES: CN(C(=O)CO)c1ccccc1-c1cnc(Nc2ccc(-c3cnco3)c(Cl)c2)o1

InChI Key: InChIKey=UDJQZKOQRHRHER-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50129106   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Inosine Monophosphate Dehydrogenase Type 2 (IMPDH2) (Homo sapiens (Human))	BDBM50129106 (CHEMBL63122 | N-{2-[2-(3-Chloro-4-oxazol-5-yl-phen...) Show SMILES CN(C(=O)CO)c1ccccc1-c1cnc(Nc2ccc(-c3cnco3)c(Cl)c2)o1 Show InChI InChI=1S/C21H17ClN4O4/c1-26(20(28)11-27)17-5-3-2-4-15(17)19-10-24-21(30-19)25-13-6-7-14(16(22)8-13)18-9-23-12-29-18/h2-10,12,27H,11H2,1H3,(H,24,25)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	41	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibition of inosine-5'-monophosphate dehydrogenase 2.				Bioorg Med Chem Lett 13: 2059-63 (2003) BindingDB Entry DOI: 10.7270/Q22Z14X1
					More data for this Ligand-Target Pair