BDBM50129112 1-[4-(4-Methyl-oxazol-5-yl)-phenyl]-3-m-tolyl-urea::CHEMBL302224

SMILES: Cc1ncoc1-c1ccc(NC(=O)Nc2cccc(C)c2)cc1

InChI Key: InChIKey=DLMYCCWASJWZCC-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50129112   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Inosine Monophosphate Dehydrogenase Type 2 (IMPDH2) (Homo sapiens (Human))	BDBM50129112 (1-[4-(4-Methyl-oxazol-5-yl)-phenyl]-3-m-tolyl-urea...) Show SMILES Cc1ncoc1-c1ccc(NC(=O)Nc2cccc(C)c2)cc1 Show InChI InChI=1S/C18H17N3O2/c1-12-4-3-5-16(10-12)21-18(22)20-15-8-6-14(7-9-15)17-13(2)19-11-23-17/h3-11H,1-2H3,(H2,20,21,22)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	500	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibition of inosine-5'-monophosphate dehydrogenase 2.				Bioorg Med Chem Lett 13: 2059-63 (2003) BindingDB Entry DOI: 10.7270/Q22Z14X1
					More data for this Ligand-Target Pair