BDBM50129194 (2S)-2-amino-4-(hydroxyamino)-4-oxobutanoic acidN(4)-hydroxy-L-asparagine::CHEMBL63902::L-Asparaginsaeure-4-hydroxyamid::L-aspartic acid beta-hydroxamate::beta-L-Aspartylhydroxamate::beta-L-aspartylhydroxamic acid::beta-aspartohydroxamic acid
SMILES: N[C@@H](CC(=O)NO)C(O)=O
InChI Key: InChIKey=ZBYVTTSIVDYQSO-REOHCLBHSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Serine racemase (Mus musculus) | BDBM50129194 ((2S)-2-amino-4-(hydroxyamino)-4-oxobutanoic acidN(...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase CHEMBL KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | 1.90E+6 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Institute of Organic Chemistry and Biochemistry of the ASCR Curated by ChEMBL | Assay Description Inhibition of mouse brain serine racemase | J Med Chem 52: 6032-41 (2009) Article DOI: 10.1021/jm900775q BindingDB Entry DOI: 10.7270/Q29G5NRV | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serine racemase (Mus musculus) | BDBM50129194 ((2S)-2-amino-4-(hydroxyamino)-4-oxobutanoic acidN(...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase CHEMBL KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 1.30E+6 | n/a | n/a | n/a | n/a | n/a | n/a |
Institute of Organic Chemistry and Biochemistry of the ASCR Curated by ChEMBL | Assay Description Inhibition of mouse recombinant serine racemase expressed in Escherichia coli MC1061 assessed as formation of D-serine after 30 mins by HPLC analysis | J Med Chem 52: 6032-41 (2009) Article DOI: 10.1021/jm900775q BindingDB Entry DOI: 10.7270/Q29G5NRV | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutamate carboxypeptidase II (Homo sapiens (Human)) | BDBM50129194 ((2S)-2-amino-4-(hydroxyamino)-4-oxobutanoic acidN(...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | PubMed | n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Guilford Pharmaceuticals Inc. Curated by ChEMBL | Assay Description Inhibition of Glutamate carboxypeptidase II | Bioorg Med Chem Lett 13: 2097-100 (2003) BindingDB Entry DOI: 10.7270/Q2Z60NF2 | |||||||||||
More data for this Ligand-Target Pair |